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Various Themes in “Of Mice and Men” In the novel “Of Mice and Men”, there were many different themes that John Steinbeck chose to include. One of the themes was misfits, outcasts and defectives, represented by the characters Lennie, Crooks and Candy. Lennie represented a misfit because he did not fit in with all the other people because of his brain capacity. Because Lennie had the brain capacity of a small child, many people thought he was crazy. George was one of the only people that understood Lennie and that is because he knew about his disability